Relevant Publications

Relevant Publications

Platinum-based therapies remain one of the mainstays of modern treatment regimens in clinical oncology. Latest research has demonstrated the targeted actions of platinums in killing cancer cells, and satraplatin in particular is a precision platinum for haemato-oncology indications.

The rediscovery of platinum-based cancer therapy

The rediscovery of platinum-based cancer therapy

Platinum (Pt) compounds entered the clinic as anticancer agents when cisplatin was approved in 1978. More than 40 years later, even in the era of precision medicine and immunotherapy…

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Platinum-(IV)-derivative satraplatin…

Platinum-(IV)-derivative satraplatin…

Platinum-(IV)-derivative satraplatin represents a new generation of orally available anti-cancer drugs that are under development for the treatment of several cancers. Understanding the mechanisms of cell cycle modulation and apoptosis is…

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Promising activity of nelfinavir-…

Promising activity of nelfinavir-…

Treatment of proteasome inhibitor (PI)-refractory multiple myeloma (MM) is challenging, with response rates of only 15% to 35% being achieved with next-generation drugs such as pomalidomide, carfilzomib, and daratumumab, alone…

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