News & Publications

News & Publications

Platinum-based therapies remain one of the mainstays of modern treatment regimens in clinical oncology. Latest research has demonstrated the targeted actions of platinums in killing cancer cells, and satraplatin in particular is a precision platinum for haemato-oncology indications.

Anticancer Research: Satraplatin Demonstrates High Cytotoxic Activity…

Anticancer Research: Satraplatin Demonstrates High Cytotoxic Activity…

Satraplatin is an oral pl​atinum analog with proven clinical efficacy and a more favorable toxicity profile, although with increased hematotoxicity, when compared to cisplatin…

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Nature Reviews: The rediscovery of platinum-based cancer therapy

Nature Reviews: The rediscovery of platinum-based cancer therapy

Platinum (Pt) compounds entered the clinic as anticancer agents when cisplatin was approved in 1978. More than 40 years later, even in the era of precision medicine and immunotherapy…

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Nature Reviews: Platinum-(IV)-derivative satraplatin…

Nature Reviews: Platinum-(IV)-derivative satraplatin…

Platinum-(IV)-derivative satraplatin represents a new generation of orally available anti-cancer drugs that are under development for the treatment of several cancers. Understanding the mechanisms of cell cycle modulation and apoptosis is…

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American Society of Hematology: Promising activity of nelfinavir-…

American Society of Hematology: Promising activity of nelfinavir-…

Treatment of proteasome inhibitor (PI)-refractory multiple myeloma (MM) is challenging, with response rates of only 15% to 35% being achieved with next-generation drugs such as pomalidomide, carfilzomib, and daratumumab, alone…

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Yahoo! Finance: Dayton Therapeutics Discovers New…

Yahoo! Finance: Dayton Therapeutics Discovers New…

Dayton Therapeutics has announced that the company is using its AI-powered genetic and molecular research model for investigating new therapeutic uses of clinical stage drug candidates where development has been discontinued – in particular satraplatin. Satraplatin is…

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Markets Insider: Dayton Therapeutics Discovers New…

Markets Insider: Dayton Therapeutics Discovers New…

Dayton Therapeutics has announced that the company is using its AI-powered genetic and molecular research model for investigating new therapeutic uses of clinical stage drug candidates where development has been discontinued – in particular satraplatin. Satraplatin is…

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Bloomberg UK: Dayton Therapeutics Discovers New…

Bloomberg UK: Dayton Therapeutics Discovers New…

Dayton Therapeutics has announced that the company is using its AI-powered genetic and molecular research model for investigating new therapeutic uses of clinical stage drug candidates where development has been discontinued – in particular satraplatin. Satraplatin is…

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Market Watch: Dayton Therapeutics Discovers New…

Market Watch: Dayton Therapeutics Discovers New…

Dayton Therapeutics has announced that the company is using its AI-powered genetic and molecular research model for investigating new therapeutic uses of clinical stage drug candidates where development has been discontinued – in particular satraplatin. Satraplatin is…

Read more